Determinations of total protein level in urine and CSF are used to diagnose and monitor clinical conditions associated with abnormal proteins concentrations. Increased total protein level in urine can be observed in majority of renal diseases (e.g. nephropathy, nephrotic syndrome, nephrosclerosis) as well as in systemic diseases such as diabetes mellitus and lupus erythematosus which frequently cause glomerular injury and heavy proteinuria. Malaria, drugs (penicillamine), malignant hypertension, amyloidosis, toxemia of pregnancy, heavy metals (gold, mercury), sickle cell disease, neoplasia in general, renal transplant rejection are additional causes of heavy proteinuria. Increased total protein level in cerebrospinal fluid can be observed in increased blood–CSF permeability caused by meningitis, endocrine/metabolic disorders (e.g. diabetic neuropathy), CSF circulation defects (e.g. mechanical obstruction - tumor, abscess, herniated disk), increased immunoglobulin IgG synthesis (e.g. multiple sclerosis), neurosyphilis.



direct, colorimetric with pyrogallol red


CSF, urine

On board stability

up to 12 weeks

Calibration stability

up to 12 weeks

Measuring range

1.6-210 mg/dl

Regulatory status


Reagent lines

  • Multipurpose Line
    Liquick Cor-URINE PROTEINS 30
    Liquick Cor-URINE PROTEINS 60

  • ACCENT-200

  • ACCENT-300

  • A-400

  • A-800

  • Prestige 24i
    Prestige 24i URINE PROTEINS (24 positions reagent tray)
    Prestige 24i URINE PROTEINS (36 positions reagent tray)

  • B50

Panels: routine screening, renal

Available reagents

The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.

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PZ Cormay S.A.

Ursynów Business Park
303 Pulawska Street
02-785 Warsaw, Poland