Cardiac biomarkers are substances that are released into the blood when the heart is damaged or stressed. These markers include enzymes, hormones, and proteins. Measurements of cardiac biomarkers are used to help diagnose acute coronary syndrome (ACS) and cardiac ischemia, conditions associated with insufficient blood flow to the heart. Tests for cardiac biomarkers can also be used to help determine a person's risk of having these conditions or to help monitor and manage someone with suspected ACS and cardiac ischemia.
Cardiac biomarker tests must be available to a health practitioner 24 hours a day, 7 days a week. Some of the tests may be performed at the point of care (POC) – in the emergency department or at a person's bedside. Usually, multiple cardiac biomarker tests are done over several hours to ensure that a rise in blood levels is not missed and to estimate the severity of a heart attack.
Cardiac Troponin T, troponin I, CK, CK-MB, MYOGLOBIN are basic biomarkers used for diagnosing and monitoring acute coronary syndrome. Increased CK-MB serum level is a strong marker of myocardial infarction. The determination of serum Myoglobin level is useful in the diagnosis of myocardial infarction, muscular dystrophy, myositis and myopathy, and also for the assessment of treatment and disease prognosis.
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The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.
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