Iron is a necessary nutrient. Increased iron level can be observed in hepatic iron overload (hemochromatosis), neonatal hemochromatosis, aceruloplasminemia, hypotransferrinemia, microcytic anemia with iron loading, sideroblastic anemia, ferroprotein disease, β-thalassemia. Long-term transfusion in persons treated for severe aplastic anemia, Blackfan-Diamond syndrome, Fanconi anemia, acute leukemia, autoimmune hemolytic anemias can also cause increased iron level. Decreased values can be observed in iron deficiency anemia, anemia of chronic disease (observed in patients with infectious and inflammatory diseases - chronic kidney disease, inflammatory bowel disease, chronic heart failure, malignancies, and hepatic diseases), gastrointestinal tumors (blood losses), IRIDA rare (autosomal recessive) inherited disorder and obesity.
colorimetric with ferrozine, without deproteinization
Specimen
serum
On board stability
up to 12 weeks (1)
Calibration stability
up to 12 weeks (1)
Measurement range
2.0-1300 µg/dL (0.36-232.7 µmol/L) (1)
Regulatory status
CE IVD
Storage temperature (2)
2-8°C
(1) These results apply to the ACCENT MC240 analyser. Results may vary when a different instrument is used.
(2) For proper storage, follow the recommended temperature range available on the label. Full details are provided in the Instructions for Use/User Manual. Transport and store at a controlled temperature in accordance with the product labeling. Deviations from the required conditions may affect the quality of the reagent.
The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.
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