GAMMA-GLUTAMYLOTRANSFERASE

Gamma-Glutamylotransferase (GGT) is an enzyme primarily found in liver. Determination of GGT activity in serum or plasma is mainly used as an aid in diagnosis and monitoring of acute and chronic diseases of the liver, bile ducts and pancreas. A significant increase in the activity of the enzyme is observed in such liver diseases as: cancer, alcohol damage, cirrhosis, inflammation (both acute and chronic). It is also a sensitive indicator of inflammation of the bile ducts or the gallbladder. Measurement of GGT activity is used to monitor abstinence in alcoholics during drug addiction treatment and to monitor the hepatotoxicity of drugs in chemically treated cancer patients.

Specification

Method:

according to the International Federation of Clinical Chemistry (IFCC), kinetic with L-γ-glutamyl-3-carboxy-4-nitroanilide

Specimen:

serum, plasma

On board stability:

up to 12 weeks

Calibration stability:

up to 12 weeks

Measuring range:

linear up to 1200 U/l

Regulatory status:

CE IVD

Reagent lines

  • Multipurpose Line
    Liquick Cor-GGT 30
    Liquick Cor-GGT 60
    Liquick Cor-GGT 120

  • ACCENT-200

  • ACCENT-300

  • A-400

  • A-800

  • Prestige 24i
    Prestige 24i LQ GGT (24 positions reagent tray)
    Prestige 24i LQ GGT (36 positions reagent tray)

  • Biolis 50i

  • OS

  • HC

Panels: hepatic, routine screening, pregnancy

Available reagents

The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.

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Contact

PZ Cormay S.A.

Ursynów Business Park,
Poland, 02-785 Warsaw,
303 Pulawska Street