CREATINE KINASE-MB

Creatine kinase (CK) catalyzes the transfer of phosphate group between creatine phosphate and adenosine diphosphate (ADP). The product of this reaction is adenosine triphosphate (ATP) – molecular source of energy. CK is a dimmer, composed of two different subunits called M and B. Three different isoenzymes formed from these subunits are found in brain and smooth muscle (BB), skeletal muscle (MM) and cardiac muscle (MM and MB). Determinations of creatine kinase MB isoenzyme (CK-MB) activity in serum are used to diagnose myocardial infarction and monitor myocardial infarction treatment. Increased creatine kinase MB isoenzyme activity can be also observed in skeletal muscle injury, chronic renal failure, overactive thyroid gland and ischemic stroke. 

Specification

Method

optimized kinetic, according to the International Federation of Clinical Chemistry (IFCC)

Specimen

serum

On board stability

up to 12 weeks

Calibration stability

up to 12 weeks

Measuring range

linear up to 4500 U/l

Regulatory status

CE IVD

Reagent lines

  • Multipurpose Line
    Liquick Cor-CK-MB 30
    Liquick Cor-CK-MB 120

  • ACCENT-200

  • ACCENT-300

  • A-400

  • A-800

  • Prestige 24i
    Prestige 24i LQ CK-MB (24 positions reagent tray)
    Prestige 24i LQ CK-MB (36 positions reagent tray)

  • Biolis 50i

  • OS

  • HC

Panels: routine screening, cardiac

Available reagents

The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.

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Contact

PZ Cormay S.A.

Ursynów Business Park,
Poland, 02-785 Warsaw,
303 Pulawska Street