CREATINE KINASE

Creatine kinase (CK) catalyzes the transfer of phosphate group between creatine phosphate and adenosine diphosphate (ADP). Determinations of creatine kinase activity in serum are used to diagnose and monitor muscular injuries. It is also used as an aid in diagnosis of clinical conditions associated with abnormal creatine kinase activity. Increased creatine kinase activity can be observed in myocardial infarction, viral myositis, polymyositis and other muscle inflammations, muscular dystrophy, malignant hyperthermia, acute rhabdomyolysis, muscle injuries, circulatory disorders, overactive thyroid gland or kidney failure. High creatine kinase activity may also occur in infectious diseases (e.g. typhoid fever), prostate, kidney, ovary and gallbladder cancers, after surgical procedures and in damage of the muscle tissue as a consequence of intense training.

Specification

Method

optimized kinetic, according to the International Federation of Clinical Chemistry (IFCC)

Specimen

serum

On board stability

up to 12 weeks

Calibration stability

up to 12 weeks

Measuring range

linear up to 3100 U/l

Regulatory status

CE IVD

Reagent lines

  • Multipurpose Line
    Liquick Cor-CK 30
    Liquick Cor-CK 60
    Liquick Cor-CK 120

  • ACCENT-200

  • ACCENT-300

  • A-400

  • A-800

  • Prestige 24i
    Prestige 24i LQ CK (24 positions reagent tray)
    Prestige 24i LQ CK (36 positions reagent tray)

  • Biolis 50i

  • OS

  • HC

Panels:  routine screening, cardiac

Available reagents

The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.

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Contact

PZ Cormay S.A.

Ursynów Business Park,
Poland, 02-785 Warsaw,
303 Pulawska Street