CREATINE KINASE
Creatine kinase (CK) catalyzes the transfer of phosphate group between creatine phosphate and adenosine diphosphate (ADP). Determinations of creatine kinase activity in serum are used to diagnose and monitor muscular injuries. It is also used as an aid in diagnosis of clinical conditions associated with abnormal creatine kinase activity. Increased creatine kinase activity can be observed in myocardial infarction, viral myositis, polymyositis and other muscle inflammations, muscular dystrophy, malignant hyperthermia, acute rhabdomyolysis, muscle injuries, circulatory disorders, overactive thyroid gland or kidney failure. High creatine kinase activity may also occur in infectious diseases (e.g. typhoid fever), prostate, kidney, ovary and gallbladder cancers, after surgical procedures and in damage of the muscle tissue as a consequence of intense training.
Specification
Method |
optimized kinetic, according to the International Federation of Clinical Chemistry (IFCC) |
Specimen |
serum |
On board stability |
up to 12 weeks |
Calibration stability |
up to 12 weeks |
Measuring range |
linear up to 3100 U/l |
Regulatory status |
CE IVD |
Reagent lines
Multipurpose Line
Liquick Cor-CK 30
Liquick Cor-CK 60
Liquick Cor-CK 120ACCENT-200
ACCENT-300
A-400
A-800
Prestige 24i
Prestige 24i LQ CK (24 positions reagent tray)
Prestige 24i LQ CK (36 positions reagent tray)B50
OS
HC
Panels: routine screening, cardiac
Available reagents
A-800 CK
ACCENT-200 CK
ACCENT-300 CK
B50-CK
HC-CK
LIQUICK COR-CK
OS-CK
PRESTIGE 24i LQ CK
The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.

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