Aspartate aminotransferase (ASAT, AST, GOT) is an enzyme widely present in tissue especially liver, heart and skeletal muscle Determinations of elevated ASAT activity in serum and plasma are mainly used to aid in the diagnosis and monitor of liver diseases e.g. hepatitis, hepatic cirrhosis, drug-induced liver injury, hepatic metastasis, mononucleosis. Also skeletal muscle diseases such as muscle trauma, surgery, burns, muscular dystrophy, heat stroke and other diseases such as acute hemolytic anemia, acute pancreatitis and patients with higher risk of COVID-19 adverse outcome. Decreased levels of ASAT can be observed in acute renal disease, beriberi, diabetic ketoacidosis, pregnancy, chronic renal dialysis.
The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.
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