Alkaline phosphatase (ALP) is an enzyme found in many tissues, especially bone, intestine, kidney and liver. Determinations of ALP activity in serum and plasma are mainly used as an aid in diagnosis, differentiation and monitoring of hepatobiliary disease and bone diseases.
Elevated levels of the enzyme in the blood are observed, e.g. in cholestatic liver diseases, osteoporosis or Paget's disease. Decreased ALP levels are associated with Wilson's disease, hypophosphatasia and deficiency of magnesium, zinc and vitamin B12.
Measurement of ALP activity is also used as a predictive marker in outcomes (death or liver transplantation) of patients with primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC).



Kinetic method recommended by International Federation of Clinical Chemistry (IFCC)


serum, plasma

On board stability

up to 12 weeks

Calibration stability

up to 2 weeks

Measuring range

linear up to 1560 U/l

Regulatory status


Reagent lines

  • Multipurpose Line
    Liquick Cor-ALP 30
    Liquick Cor-ALP 60
    Liquick Cor- ALP 120

  • ACCENT-200

  • ACCENT-300

  • A-400

  • A-800

  • Prestige 24i
    Prestige 24i LQ ALP (24 positions reagent tray)
    Prestige 24i LQ ALP (36 positions reagent tray)

  • B50

  • OS

  • HC

Panels: routine screening, bone metabolism, hepatic, pregnancy

Available reagents

The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.

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303 Pulawska Street
02-785 Warsaw, Poland