Alanine aminotransferase (ALAT, ALT, GPT) is an enzyme primarily found in liver. Determinations of elevated ALAT activity in serum and plasma are mainly used to aid in the diagnosis and monitor of liver diseases e.g. acute hepatitis, hepatocyte necrosis, hepatic ischemia, cirrhosis, cholestasis, liver tumor, hepatotoxic drugs, mechanical jaundice. Increased levels of ALAT can be observed in severe burns, striated muscle injury, muscle inflammation, pancreatitis, myocardial infarction, infectious mononucleosis, trauma, patients with higher risk of COVID-19 adverse outcome.
The specification was based on data determined on selected analyzers. We recommend that all users should refer to the instruction for use (IFU) and instruments’ user or service manuals before proceeding.
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